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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
16.06
Human Site:
T918
Identified Species:
29.44
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
T918
K
D
E
S
L
P
C
T
I
T
D
V
W
I
S
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
T918
K
D
E
S
L
P
C
T
I
T
D
V
W
I
S
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
T918
K
D
E
S
L
P
C
T
V
T
D
V
W
I
S
Dog
Lupus familis
XP_543184
1286
146207
T946
K
D
G
S
L
P
C
T
I
I
D
V
W
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
V870
L
P
P
V
L
N
D
V
W
T
R
E
K
E
A
Rat
Rattus norvegicus
NP_001099552
648
74414
E331
Y
G
D
K
K
L
L
E
K
K
P
P
P
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
L547
N
R
E
E
R
K
V
L
E
K
K
H
K
A
K
Chicken
Gallus gallus
XP_420401
1281
145243
N938
K
E
F
P
I
A
V
N
E
V
W
V
K
E
K
Frog
Xenopus laevis
Q7ZZC8
944
104521
G627
L
G
I
N
L
L
G
G
P
L
G
G
K
Q
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
V380
E
P
T
L
P
G
A
V
E
Q
M
Q
P
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
S774
D
G
K
Q
S
G
D
S
K
E
A
A
D
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
R289
P
E
S
E
S
A
R
R
N
S
F
P
E
Q
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
S541
E
A
E
A
L
V
P
S
P
K
R
I
T
K
S
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
93.3
86.6
N.A.
13.3
0
N.A.
6.6
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
20
6.6
N.A.
6.6
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
16
8
0
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% C
% Asp:
8
31
8
0
0
0
16
0
0
0
31
0
8
0
0
% D
% Glu:
16
16
39
16
0
0
0
8
24
8
0
8
8
16
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
24
8
0
0
16
8
8
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
8
0
8
0
0
0
24
8
0
8
0
31
0
% I
% Lys:
39
0
8
8
8
8
0
0
16
24
8
0
31
16
16
% K
% Leu:
16
0
0
8
54
16
8
8
0
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
8
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
8
16
8
8
8
31
8
0
16
0
8
16
16
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
8
0
24
0
% Q
% Arg:
0
8
0
0
8
0
8
8
0
0
16
0
0
0
8
% R
% Ser:
0
0
8
31
16
0
0
16
0
8
0
0
0
0
39
% S
% Thr:
0
0
8
0
0
0
0
31
0
31
0
0
8
0
0
% T
% Val:
0
0
0
8
0
8
16
16
8
8
0
39
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
8
0
31
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _